Rutin, a polyphenol flavonoid glycoside found in citrus and other plants, combines the benefits of quercetin and rutinose. Renowned in cosmetics for its potent antioxidant, antibacterial, and wound-healing properties, it rivals ascorbic acid in efficacy. While studies suggest its potential as a skin-whitener and SPF enhancer, its primary acclaim lies in bolstering the skin’s defense against sun damage through its formidable free radical-scavenging abilities.
Rutin (rutoside, quercetin-3-O-rutinoside or sophorin) is the glycoside combining the flavonol quercetin and the disaccharide rutinose (α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranose). It is a flavonoid glycoside found in a wide variety of plants, including citrus.
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IUPAC name
3′,4′,5,7-Tetrahydroxy-3-[α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyloxy]flavone
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Systematic IUPAC name
(42S,43R,44S,45S,46R,72R,73R,74R,75R,76S)-13,14,25,27,43,44,45,73,74,75-Decahydroxy-76-methyl-24H-3,6-dioxa-2(2,3)-[1]benzopyrana-4(2,6),7(2)-bis(oxana)-1(1)-benzenaheptaphane-24-one | |
Other names
Rutoside (INN)
Phytomelin Sophorin Birutan Eldrin Birutan Forte Rutin trihydrate Globularicitrin Violaquercitrin Quercetin rutinoside | |
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3D model (JSmol)
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DrugBank | |
ECHA InfoCard | 100.005.287 |
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PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C27H30O16 | |
Molar mass | 610.521 g·mol−1 |
Appearance | Solid |
Melting point | 242 °C (468 °F; 515 K) |
12.5 mg/100 mL 13 mg/100mL | |
Pharmacology | |
C05CA01 (WHO) | |
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NFPA 704 (fire diamond) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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