Resveratrol

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Resveratrol is a type of natural phenol and a potent polyphenolic antioxidant produced by several plants such as grapes, blueberries, raspberries, mulberries, and peanuts. Topical application helps protect the skin’s surface, interrupts and helps protect against environmental influences, and brightens a tired-looking complexion. Resveratol has many skin-calming properties that may help minimize the appearance of redness.

Resveratrol (Wikipedia)

Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury or when the plant is under attack by pathogens, such as bacteria or fungi. Sources of resveratrol in food include the skin of grapes, blueberries, raspberries, mulberries, and peanuts.

Resveratrol
Chemical 9–69 structure of trans-resveratrol
Chemical structure of trans-resveratrol
Chemical structures of cis- and trans-resveratrols
Chemical structures of cis- ((Z)-resveratrol, left) and trans-resveratrol ((E)-resveratrol, right)
Names
Preferred IUPAC name
5-[(E)-2-(4-Hydroxyphenyl)ethen-1-yl]benzene-1,3-diol
Other names
trans-3,5,4′-Trihydroxystilbene;
3,4′,5-Stilbenetriol;
trans-Resveratrol;
(E)-5-(p-Hydroxystyryl)resorcinol;
(E)-5-(4-hydroxystyryl)benzene-1,3-diol
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.121.386 Edit this at Wikidata
KEGG
RTECS number
  • CZ8987000
UNII
  • InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+ checkY
    Key: LUKBXSAWLPMMSZ-OWOJBTEDSA-N checkY
  • InChI=1/C14H12O3/c15-
    12-5-3-10(4-6-12)
    1-2-11-7-13(16)9-
    14(17)8-11/h1-9,15-
    17H/b2-1+
  • Oc1ccc(cc1)\C=C\c2cc(O)cc(O)c2
Properties
C14H12O3
Molar mass 228.247 g·mol−1
Appearance white powder with
slight yellow cast
Melting point 261 to 263 °C (502 to 505 °F; 534 to 536 K)
Solubility in water 0.03 g/L
Solubility in DMSO 16 g/L
Solubility in ethanol 50 g/L
UV-vismax) 304nm (trans-resveratrol, in water)
286nm (cis-resveratrol, in water)
Hazards
GHS labelling:
GHS07: Exclamation mark
Warning
H319
P264, P280, P305+P351+P338, P337+P313
Lethal dose or concentration (LD, LC):
23.2 μM (5.29 g)
Safety data sheet (SDS) Fisher Scientific
Sigma Aldrich
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)
UV visible spectrum of trans-resveratrol

Although commonly used as a dietary supplement and studied in laboratory models of human diseases, there is no high-quality evidence that resveratrol improves lifespan or has a substantial effect on any human disease.

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