N-hydroxysuccinimide is a synthetic ingredient used in cosmetics as an ester to soften and condition skin. It’s also a reagent, a substance used to trigger a reaction that leads to a new substance, such as peptides and polymers. N-hydroxysuccinimide activates the elimination of blood originated pigments responsible for dark color and inflammation that causes under eye circles.
N-Hydroxysuccinimide (NHS) is an organic compound with the formula (CH2CO)2NOH. It is a white solid that is used as a reagent for preparing active esters in peptide synthesis. It can be synthesized by heating succinic anhydride with hydroxylamine or hydroxylamine hydrochloride.
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Names | |||
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Preferred IUPAC name
1-Hydroxypyrrolidine-2,5-dione | |||
Other names
HOSu, HSI.
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Identifiers | |||
3D model (JSmol)
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ChemSpider | |||
ECHA InfoCard | 100.025.456 | ||
PubChem CID
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UNII | |||
CompTox Dashboard (EPA)
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Properties | |||
C4H5NO3 | |||
Molar mass | 115.09 g/mol | ||
Appearance | Colourless solid | ||
Melting point | 95 °C (203 °F; 368 K) | ||
Related compounds | |||
Related imides
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Succinimide N-Bromosuccinimide | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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