EDTA (ethylenediaminetetraacetic acid) is a very common additive in products that helps them stay in good condition for longer. It works by counteracting the metal ions that enter the formula from the water, which would otherwise lead to some undesired changes. It is generally added in small amounts, approximately 0.1% or less, and its purpose is to act as a chelating agent to reduce the activity of the metal ions that might be found in the product.
Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid with the formula [CH2N(CH2CO2H)2]2. This white, water-soluble solid is widely used to bind to iron (Fe2+/Fe3+) and calcium ions (Ca2+), forming water-soluble complexes even at neutral pH. It is thus used to dissolve Fe- and Ca-containing scale as well as to deliver iron ions under conditions where its oxides are insoluble. EDTA is available as several salts, notably disodium EDTA, sodium calcium edetate, and tetrasodium EDTA, but these all function similarly.
Names | |
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Preferred IUPAC name
2,2′,2′′,2′′′-(Ethane-1,2-diyldinitrilo)tetraacetic acid | |
Other names
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Identifiers | |
3D model (JSmol)
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Abbreviations | EDTA, H4EDTA |
1716295 | |
ChEBI | |
ChEMBL | |
ChemSpider | |
DrugBank | |
ECHA InfoCard | 100.000.409 |
EC Number |
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144943 | |
KEGG | |
MeSH | Edetic+Acid |
PubChem CID
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RTECS number |
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UNII |
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UN number | 3077 |
CompTox Dashboard (EPA)
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Properties | |
C10H16N2O8 | |
Molar mass | 292.244 g·mol−1 |
Appearance | Colourless crystals |
Density | 0.860 g cm−3 (at 20 °C) |
log P | −0.836 |
Acidity (pKa) | 2.0, 2.7, 6.16, 10.26 |
Thermochemistry | |
Std enthalpy of
formation (ΔfH⦵298) |
−1765.4 to −1758.0 kJ mol−1 |
Std enthalpy of
combustion (ΔcH⦵298) |
−4461.7 to −4454.5 kJ mol−1 |
Pharmacology | |
S01XA05 (WHO) V03AB03 (WHO) (salt) | |
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Hazards | |
GHS labelling: | |
Warning | |
H319 | |
P305+P351+P338 | |
NFPA 704 (fire diamond) | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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1000 mg/kg (oral, rat) |
Related compounds | |
Related alkanoic acids
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Related compounds
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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