Chrysin is a natural flavanoid that’s well documented for exhibiting anti-inflammatory capabilities. In skin care, this ingredient is mostly used as a skin conditioning agent, anti-inflammatory and potential antioxidant.
Chrysin, also called 5,7-dihydroxyflavone, is a flavone found in honey, propolis, the passion flowers, Passiflora caerulea and Passiflora incarnata, and in Oroxylum indicum. It is extracted from various plants, such as the blue passion flower (Passiflora caerulea). Following oral intake by humans, chrysin has low bioavailability and rapid excretion. It is under basic research to evaluate its safety and potential biological effects.
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| Names | |
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| IUPAC name
5,7-Dihydroxyflavone
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| Preferred IUPAC name
5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one | |
| Other names
NP-005901; Galangin flavanone
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| Identifiers | |
3D model (JSmol)
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| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.006.864 |
| KEGG | |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C15H10O4 | |
| Molar mass | 254.241 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chrysin is an ingredient in dietary supplements. As of 2016, there was no clinical use of chrysin, and no evidence for its effect on testosterone levels. In 2016, the US Food and Drug Administration did not recommend chrysin be included on the list of bulk drug substances that can be used in compounding under section 503A of the Federal Food, Drug, and Cosmetic Act.
