Acetone

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A solven often used in the manufacture of nail polish removers. These types of solvents (i.e., methyl butyl, and amyl) are also used to chemically extract oils from herbs and in other cosmetic areas. They are toxic.

Acetone (Wikipedia)

Acetone (2-propanone or dimethyl ketone), is an organic compound with the formula (CH3)2CO. It is the simplest and smallest ketone (>C=O). It is a colorless, highly volatile and flammable liquid with a characteristic pungent odour.

Acetone
Full structural formula of acetone with dimensions
Skeletal formula of acetone
Ball-and-stick model of acetone
Space-filling model of acetone
Sample of acetone
Names
IUPAC name
Acetone
Preferred IUPAC name
Propan-2-one
Systematic IUPAC name
2-Propanone
Other names
  • Acetonum
  • Dimethyl ketone
  • Dimethyl carbonyl
  • Ketone propane
  • β-Ketopropane
  • Propanone
  • 2-Propanone
  • Pyroacetic spirit (archaic)
Identifiers
3D model (JSmol)
3DMet
635680
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.000.602 Edit this at Wikidata
EC Number
  • 200-662-2
1466
KEGG
MeSH Acetone
RTECS number
  • AL3150000
UNII
UN number 1090
  • InChI=1S/C3H6O/c1-3(2)4/h1-2H3 checkY
    Key: CSCPPACGZOOCGX-UHFFFAOYSA-N checkY
  • InChI=1/C3H6O/c1-3(2)4/h1-2H3
    Key: CSCPPACGZOOCGX-UHFFFAOYAF
  • CC(=O)C
Properties
C3H6O
Molar mass 58.080 g·mol−1
Appearance Colourless liquid
Odor Pungent, irritating, floral, cucumber-like
Density 0.7845 g/cm3 (25 °C)
Melting point −94.7 °C (−138.5 °F; 178.5 K)
Boiling point 56.05 °C (132.89 °F; 329.20 K)
Miscible
Solubility Miscible in benzene, diethyl ether, methanol, chloroform, ethanol
log P −0.16
Vapor pressure
  • 9.39 kPa (0 °C)
  • 30.6 kPa (25 °C)
  • 374 kPa (100 °C)
  • 2.8 MPa (200 °C)
Acidity (pKa)
  • 19.16 (H2O)
  • 26.5 (DMSO)
−33.78·10−6 cm3/mol
1.3588 (VD = 54.46)
Viscosity 0.295 mPa·s (25 °C)
Structure
Trigonal planar at C2
Dihedral at C2
2.91 D
Thermochemistry
125.45 J/(mol·K)
200.4 J/(mol·K)
(−250.03)  (−248.77) kJ/mol
−1.772 MJ/mol
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Mildly toxic
GHS labelling:
GHS02: Flammable GHS07: Exclamation mark
Danger
H225, H302, H319, H336, H373
P210, P235, P260, P305+P351+P338
NFPA 704 (fire diamond)
1
3
0
Flash point −20 °C (−4 °F; 253 K)
465 °C (869 °F; 738 K)
Explosive limits 2.6–12.8%
1185 mg/m3 (TWA), 2375 mg/m3 (STEL)
Lethal dose or concentration (LD, LC):
  • 5800 mg/kg (rat, oral)
  • 3000 mg/kg (mouse, oral)
  • 5340 mg/kg (rabbit, oral)
20,702 ppm (rat, 8 h)
45,455 ppm (mouse, 1 h)
NIOSH (US health exposure limits):
PEL (Permissible)
1000 ppm (2400 mg/m3)
REL (Recommended)
TWA 250 ppm (590 mg/m3)
IDLH (Immediate danger)
2500 ppm
Related compounds
Related compounds
Supplementary data page
Acetone (data page)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

Acetone is miscible with water and serves as an important organic solvent in its own right, in industry, home, and laboratory. About 6.7 million tonnes were produced worldwide in 2010, mainly for use as a solvent and production of methyl methacrylate (and from that PMMA) as well as bisphenol A. It is a common building block in organic chemistry. Familiar household uses of acetone are as the active ingredient in nail polish remover and as paint thinner. It has volatile organic compound (VOC) exempt status in the United States.

Acetone is produced and disposed of in the human body through normal metabolic processes. It is normally present in blood and urine. People with diabetic ketoacidosis produce it in larger amounts. Ketogenic diets that increase ketone bodies (acetone, β-hydroxybutyric acid and acetoacetic acid) in the blood are used to counter epileptic attacks in infants and children who suffer from refractory epilepsy.

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