Derived from fruit and/or algae to stabilize and give a lubricant feeling to lotions. It is non-toxic.
Sorbitol (/ˈsɔː(r)bɪtɒl/), less commonly known as glucitol (/ˈɡluːsɪtɒl/), is a sugar alcohol with a sweet taste which the human body metabolizes slowly. It can be obtained by reduction of glucose, which changes the converted aldehyde group (−CHO) to a primary alcohol group (−CH2OH). Most sorbitol is made from potato starch, but it is also found in nature, for example in apples, pears, peaches, and prunes. It is converted to fructose by sorbitol-6-phosphate 2-dehydrogenase. Sorbitol is an isomer of mannitol, another sugar alcohol; the two differ only in the orientation of the hydroxyl group on carbon 2. While similar, the two sugar alcohols have very different sources in nature, melting points, and uses.
Names | |
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IUPAC name
(2S,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexol
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Other names
D-glucitol; D-Sorbitol; Sorbogem; Sorbo
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Identifiers | |
3D model (JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
DrugBank | |
ECHA InfoCard | 100.000.056 |
E number | E420 (thickeners, ...) |
KEGG | |
MeSH | Sorbitol |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C6H14O6 | |
Molar mass | 182.17 g/mol |
Appearance | White crystalline powder |
Density | 1.49 g/cm3 |
Melting point | 94–96 °C (201–205 °F; 367–369 K) |
2350 g/L | |
log P | -4.67 |
-107.80·10−6 cm3/mol | |
Pharmacology | |
A06AD18 (WHO) A06AG07 (WHO) B05CX02 (WHO) V04CC01 (WHO) | |
Hazards | |
NFPA 704 (fire diamond) | |
Flash point | > 100 °C (212 °F; 373 K) |
420 °C (788 °F; 693 K) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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As an over-the-counter drug, sorbitol is used as a laxative to treat constipation.